The unexpected gift was a nice surprise! We found the system to be the cheapest available option for our purpose. The technical staff came down and helped us with the setup. So far, the system has worked very well and we are extremely satisfied with our purchase. Savannah Branson 15 Mar 19 We bought a microplate reader from them- the equipment works great, and the technician they sent out to install it and teach us how to use it was great.
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Have purchased from GMI before and will do so again. Suzanne Nelson 25 Jun 19 I liked the communication from beginning to end. They were very prompt with setting up the service date to sending me the paper work at the end Anna Simeon 28 Jun 19 Great customer service, knowledgeable staff, AND they gave us a free upgrade on the equipment we purchased.
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We have enjoyed working with the excellent customer service. Would definitely recommend others to purchase lab equipment from here. The customer service was amazing. They helped me find the one that best fit my needs at a great price. They maintained communication throughout the entire process--ordering, shipping, and even after it was received. Overall, it was a fantastic experience! GMI has a knowledgeable staff and their customer support is very responsive.
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Great selection of UV detectors, and great service too. Will no doubt purchase from again! Thanks again. They are easy to work with, patient, and responsive to our inquiries. I've both bought and sold equipment with them and they always make the process transparent, easy, and efficient. I've found that their pricing is highly competitive too.
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Their commitment to service extended far beyond simply providing our lab equipment; we wanted a 'drop-in' solution to minimize laboratory down-time. GMI met our exacting challenge by coordinating delivery, placing equipment on the lab floor, and performing installation on the day that was specified. It was an impressive feat The equipment arrived in great condition, was placed exactly where we wanted it, and was installed and verified for use. When we embarked on building a new lab, we were looking for a vendor, but also for a partner.
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Two ampoules were initially prepared from a common master solution. One of them A2 was repeatedly opened and transferred to a new ampoule, while the other A1 was kept as a control. Figure 5 shows that, while the VIC response is gradually increasing over the course of 2 days as the solution reaches secular equilibrium, the A1 and A2 responses are equivalent.
In addition, where possible, all gravimetric dilution factors in all experiments were confirmed radiometrically.
In all cases, dilution factors agreed within uncertainties. Impurities In each experiment, ampoules were measured on high-purity germanium HPGe detectors to look for photon-emitting impurities. No impurities were detected within the following photon emission rates for a 5 mL ampoule containing approximately 1.
No corrections were made. Primary activity determinations 3. Table 3 provides a detailed uncertainty budget. In E2, the combined standard uncertainty was mostly due to within- and between-insertion where a single insertion refers to placing the source into the counter once measurement variability. The results in E3 were comparable, but with the activity concentration appearing to trend down slightly with time embodied in both the counting uncertainty and the between-source variance, since one source was counted after the other.
Such a trend could arise from cocktail instability due to the use of water instead of 1. By diluting the acid content in the aqueous phase of the cocktails, the solubility of Ra and its progeny would be reduced. Finally, in E3, a much larger between-source uncertainty resulted in an overall larger combined standard uncertainty.
With only two sources, it is not clear whether any specific anomaly accounts for the variance, but the magnitude is relatively small. Uncertainties in E4 were comparable to those in E2. The calculated activities were relatively insensitive to nuclear data and efficiency model, giving a robust result with small combined standard uncertainty. Table 4 provides a detailed uncertainty budget. In E2, the within-cycle variance dominated the LS measurement precision uncertainty.
In E3, between-cycle variance was of similar magnitude to within-cycle variance, contributing to significantly larger LS measurement precision uncertainty. This is consistent with the TDCR findings, except that the trending with time is absent.
This cocktail-dependence is embodied in the LS measurement precision in Table 4. Table 5 shows how the Monte Carlo correction improved agreement between extrapolations with different gates. In E2, the combined standard uncertainty was mostly due to counting statistics. In E3, the counting uncertainty was much smaller, but between-source uncertainty which can capture statistical and systematic variances otherwise missed was larger, resulting in a combined standard uncertainty of similar magnitude.
The intercepts were relatively insensitive to nuclear data, gate selection, extrapolation type, and inefficiency domains, bolstering confidence in the robustness of the LTAC result. We are collecting and analyzing additional data, but these initial measurements appear to be consistent with the set of historical data, but not the recommended value.
The most recent Pg determinations, with smaller uncertainties especially Gehrke et al. Good between-method agreement was accompanied by good between-experiment agreement as established via IC responses. Weighted and unweighted averages were identical within the significant figures. Table 8 gives a summary of the dial settings determined for the NIST-maintained calibrators in the ampoule geometry.
The standard was further confirmed via comparison of theoretical and measured responses of ionization chambers and an automatic NaI Tl well counter. This standard will form the basis for clinically significant calibrations in other chemical forms and in other measurement geometries. Future drug products based on, e. Efforts are underway at NIST to develop measurement strategies and models for these challenging cases.
Acknowledgements We are grateful to John Keightley National Physical Labortory, UK for frequent and ongoing enthusiastic and collaborative discussions. This work was funded in part by Oncoinvent AS, Norway. EN is employed by and owns stock in Oncoinvent.
EN was supported by the Industrial PhD project n. References Agostinelli, S. Methods Phys Res A , Bateman, H, Cambridge Phil. Table of Radionuclides Vol. Monographie BIPM Bergeron, D. Bickel, A. Bobin, C. Bouchard, J.
Broda, R. Dalmasso, J. Fitzgerald, R. Gehrke, R. Kossert, K. This is consistent with the TDCR findings, except that the trending with time is absent.
This cocktail-dependence is embodied in the LS measurement precision in Table 4. Table 5 shows how the Monte Carlo correction improved agreement between extrapolations with different gates. In E2, the combined standard uncertainty was mostly due to counting statistics. In E3, the counting uncertainty was much smaller, but between-source uncertainty which can capture statistical and systematic variances otherwise missed was larger, resulting in a combined standard uncertainty of similar magnitude.
The intercepts were relatively insensitive to nuclear data, gate selection, extrapolation type, and inefficiency domains, bolstering confidence in the robustness of the LTAC result. We are collecting and analyzing additional data, but these initial measurements appear to be consistent with the set of historical data, but not the recommended value. The most recent Pg determinations, with smaller uncertainties especially Gehrke et al.
Good between-method agreement was accompanied by good between-experiment agreement as established via IC responses. Weighted and unweighted averages were identical within the significant figures. Table 8 gives a summary of the dial settings determined for the NIST-maintained calibrators in the ampoule geometry. The standard was further confirmed via comparison of theoretical and measured responses of ionization chambers and an automatic NaI Tl well counter.
This standard will form the basis for clinically significant calibrations in other chemical forms and in other measurement geometries. Future drug products based on, e. Efforts are underway at NIST to develop measurement strategies and models for these challenging cases. Acknowledgements We are grateful to John Keightley National Physical Labortory, UK for frequent and ongoing enthusiastic and collaborative discussions.
This work was funded in part by Oncoinvent AS, Norway. EN is employed by and owns stock in Oncoinvent. EN was supported by the Industrial PhD project n. References Agostinelli, S. Methods Phys Res A , Bateman, H, Cambridge Phil.
Table of Radionuclides Vol. Monographie BIPM Bergeron, D. Bickel, A. Bobin, C. Bouchard, J. Broda, R. Dalmasso, J. Fitzgerald, R. Gehrke, R. Kossert, K. Kurcewicz, W. A , Lucas, L. Calibration of the massic activity of a solution of Tc Lodge, D. Holt, P. Kinahan, D. Wong, R. Wahl, Moore, W. Shelf Res. Pappenheim, A. Peghaire, A. Methods 75, Rutherford, E. Sadasivan, S. Methods , Sibbens, G.
Wick, R. Zimmerman, B. Nichols indicated.
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